5月26日の生命環境科学系入試説明会には、生合成リデザイン公開シンポジウムへ参加するため参加できません。とは言え、研究室見学や面談は午前中のみ可能ですので、興味のある方は説明会の前に是非お越し下さい。4月21日の説明会は終日おります。また、見学は随時受け付けておりますので気軽にご連絡下さい。

 Schedule

2018.3.20-24:エジプト研究打ち合わせと微生物採集

2017.12.19:特別講義 (東京理科大学 基礎工学部 生物工学科)

2017.12.16:生合成リデザインー第3回公開シンポジウム (東工大)

2017.12.13駒場サイエンス倶楽部 “自然からの贈り物”-生物がつくり出す多様な二次代謝物

2018.12.5-7:統合自然科学実習

2017.11.20:特別講演会 13:00- 3-116, Prof. Xavier Franc (Rouen-Normandy University, France)

2017.11.16:第17回糸状菌分子生物学コンファレンス  (佐賀)

2017.10.31:特別講義 (熊本大学大学院生命科学研究部)

2017.10.02:1st China-Japan Joint Symposium on Natural Product Biosynthesis

2017.09.20:第59回天然有機化合物討論会 (札幌)

2017.08.25:生合成若手勉強会 (草津)

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 Paper for lab. seminar

*Seth B. Herzon
Molecular Basis of Gut Microbiome-Associated Colorectal Cancer: A Synthetic Perspective,
J. Am. Chem. Soc. 2017, 139, 14817–14824.

*Mohammad R. Seyedsayamdost
Discovery of scmR as a global regulator of secondary metabolism and virulence in Burkholderia thailandensis E264,
Proc. Natl. Acad. Sci. 2017, 114, 2920 –2928.

*Matthias Brock
A Non-canonical Melanin Biosynthesis Pathway Protects Aspergillus terreus Conidia from Environmental Stress,
Cell Chem. Biol. 2017, 23, 587 –597.

*Dirk Hoffmeister
Induced Chemical Defense of a Mushroom by a Double-Bond-Shifting Polyene Synthase,
Angew. Chem. Int. Ed. 2017, 56, 5937 –5941.

*Mohammad R. Seyedsayamdost
Discovery of a Cryptic Antifungal Compound from Streptomyces albusJ1074 Using High-Throughput Elicitor Screens,
J. Am. Chem. Soc. 2017139, 9203−9212.

*Chengshu Wang
Fungal Cordycepin Biosynthesis Is Coupled with the Production of the Safeguard Molecule Pentostatin,
Cell Chem. Biol. 201724, 1–11.

*Paul D. Straight
A Link between Linearmycin Biosynthesis and Extracellular Vesicle Genesis Connects Specialized Metabolism and BacterialMembrane Physiology,
Cell Chem. Biol. 201724, 1238–1249.

*Elizabeth S. Sattely
Biosynthesis of cabbage phytoalexins from indole glucosinolate,
Proc. Natl. Acad. Sci. 2017114, 1910-1915.

*Xinyu Liu
Discovery of a Calcium-Dependent Enzymatic Cascade for the Selective Assembly of Hapalindole-Type Alkaloids: On the Biosynthetic Origin of Hapalindole U,
Angew. Chem. Int. Ed. 201756, 9062 –9066.

*Gong-Li Tang
Catalysis of Extracellular Deamination by a FAD-Linked Oxidoreductase after Prodrug Maturation in the Biosynthesis of Saframycin A,
Angew. Chem. Int. Ed. 201756, 9116 –9120.

*Toshifumi Inada
Ubiquitination of stalled ribosome triggers ribosome-associated quality control,
Nature Communications 20178

*Ming JiangShuangjun Lin and Meifeng Tao
Formation of an Angular Aromatic Polyketide from a Linear Anthrene Precursor via Oxidative Rearrangement,
Cell Chem. Biol. 201724, 881-891.

*Markus Künzler
Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products,
Nature Chem. Biol. 201713, 833–835.

*Gavin J. Williams
Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering,
ACS Chem. Biol. 201712, 114–123.

*Jason M. Crawford
Domain-Targeted Metabolomics Delineates the Heterocycle Assembly Steps of Colibactin Biosynthesis,
J. Am. Chem. Soc. 2017139, 4195–4201.

*Michael A. Fischbach
Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases,
Cell 2017168, 517–526.

*Craig A. Townsend
Functional and Structural Analysis of Programmed C-Methylation in the Biosynthesis of the Fungal Polyketide Citrinin,
Cell Chem. Biol. 201724, 316-325.

*Makoto Nishiyama
Genome Mining of Amino Group Carrier Protein-Mediated Machinery: Discovery and Biosynthetic Characterization of a Natural Product with Unique Hydrazone Unit,
ACS Chem. Biol. 201712, 124–131.

*Yi Tang
Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases,
J. Am. Chem. Soc. 2017139, 5317–5320.

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Representative Publications